Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.59 |
| ▸ | SHBG | P04278 | 4/20 | 0.59 |
| ▸ | PGR | P06401 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MLNR | O43193 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10957556 | 1.00 | NR3C1 (0.59) | NR3C1SHBGPGRALDH1A1ADRA1A | |
| SCHEMBL10960072 | 0.93 | PSEN1 (0.61) | NR3C1SHBGPGRALDH1A1ADRA1A | |
| SCHEMBL10960067 | 0.93 | PSEN1 (0.61) | NR3C1SHBGPGRALDH1A1ADRA1A | |
| SCHEMBL10882598 | 0.91 | LMNA (0.59) | NR3C1SHBGPGRALDH1A1ADRA1A | |
| SCHEMBL10882603 | 0.91 | LMNA (0.59) | NR3C1SHBGPGRALDH1A1ADRA1A | |
| SCHEMBL10442550 | 0.91 | NR3C1 (0.61) | NR3C1SHBGPGRALDH1A1ADRA1A | |
| SCHEMBL10442549 | 0.91 | NR3C1 (0.61) | NR3C1SHBGPGRALDH1A1ADRA1A | |
| SCHEMBL10961047 | 0.89 | SHBG (0.64) | NR3C1SHBGPGRALDH1A1ADRA1A | |
| SCHEMBL10961041 | 0.89 | SHBG (0.64) | NR3C1SHBGPGRALDH1A1ADRA1A | |
| SCHEMBL10882344 | 0.87 | AR (0.61) | NR3C1SHBGPGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542128-A | 17α-Pregn-4-ene-3-oxo-21-carboxylic acid esters, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-09-17 | — | — | US | disclosed |
| EP-0099854-A2 | 17-Alpha-pregn-4-ene-3-oxo-21-carboxylic acid esters, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-02-01 | — | — | EP | disclosed |