Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10954956 | 0.76 | MAPT (0.62) | EPHX2MAPTTDP1L3MBTL1MEN1 | |
| SCHEMBL3859718 | 0.76 | HPGD (0.41) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL10812745 | 0.76 | EPHX2 (0.47) | EPHX2TDP1RAB9AHTTTRPV1 | |
| SCHEMBL12225782 | 0.71 | NPC1 (0.69) | EPHX2MAPTTDP1RAB9AMEN1 | |
| SCHEMBL24876167 | 0.70 | FFAR4 (0.47) | EPHX2MAPTTDP1L3MBTL1MEN1 | |
| SCHEMBL17079593 | 0.70 | EPHX2 (0.69) | EPHX2MAPTIDH1RAB9AMEN1 | |
| SCHEMBL11125111 | 0.68 | CTSC (0.56) | EPHX2MAPTTDP1L3MBTL1RAB9A | |
| SCHEMBL5535236 | 0.67 | S1PR1 (0.44) | KIF11TRPV1SCN8A | |
| SCHEMBL13680420 | 0.67 | SLC6A4 (0.58) | L3MBTL1RAB9AMEN1KMT2AHTT | |
| SCHEMBL856882 | 0.67 | L3MBTL1 (0.59) | EPHX2MAPTTDP1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497822-A | Insecticidal N-benzoyl-N'-phenyl-N'-(R-thio)ureas | SHELL OIL COMPANY (US) | 1985-02-05 | — | — | US | disclosed |