Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | BCR | P11274 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876210 | 0.84 | FFAR4 (0.45) | FFAR4EPHX2MAPTL3MBTL1KIF11 | |
| SCHEMBL24876248 | 0.79 | DHODH (0.39) | FFAR4EPHX2MAPTKDM4EL3MBTL1 | |
| SCHEMBL24876191 | 0.70 | MAPT (0.45) | FFAR4EPHX2MAPTL3MBTL1FAAH | |
| SCHEMBL31236141 | 0.70 | FFAR4 (0.64) | FFAR4MAPTKIF11TP53ALDH1A1 | |
| SCHEMBL24876157 | 0.70 | FFAR4 (0.64) | FFAR4MAPTKIF11TP53ALDH1A1 | |
| SCHEMBL10957619 | 0.70 | EPHX2 (0.45) | EPHX2MAPTKDM4ETRPV1L3MBTL1 | |
| SCHEMBL3722072 | 0.67 | FFAR4 (0.56) | FFAR4KDM4ESCN5ASCN9AKIF11 | |
| SCHEMBL11366701 | 0.66 | CA12 (0.39) | MAPTKDM4EL3MBTL1KIF11MEN1 | |
| SCHEMBL10958092 | 0.65 | MAPT (0.53) | EPHX2MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL1241806 | 0.65 | FFAR4 (0.55) | FFAR4EPHX2MAPTL3MBTL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |