Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959948 | 0.89 | P2RX7 (0.48) | P2RX7MEN1KMT2AMLNRNR1I2 | |
| SCHEMBL10826355 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2APNPPOLBALDH1A1 | |
| SCHEMBL10957916 | 0.77 | HTR2A (0.55) | MEN1KMT2ACYP3A4CYP2D6HTR2A | |
| Laprafylline SCHEMBL1150347 | 0.76 | PDE5A (0.53) | MEN1KMT2ACYP1A2CYP3A4HTR2A | |
| SCHEMBL4202515 | 0.74 | PNP (0.53) | MEN1KMT2AADORA3PNPPOLB | |
| SCHEMBL4193079 | 0.73 | PNP (0.52) | MEN1KMT2AADORA3PKMPNP | |
| SCHEMBL10961792 | 0.71 | HTR2A (0.58) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10923672 | 0.71 | PDE5A (0.53) | MEN1KMT2ACYP1A2CYP3A4HTR2A | |
| SCHEMBL10957892 | 0.70 | KMT2A (0.48) | P2RX7MEN1KMT2AMLNRNR1I2 | |
| SCHEMBL10960825 | 0.70 | MEN1 (0.47) | P2RX7MEN1KMT2AMLNRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548820-A | BRONCHODILATORS, ANTIALLERGENS, HYDROLASE ENZYME INHIBITORS, ANTIG-ANTIBODY REACTION INHIBITORS | ADIR (FR) | 1985-10-22 | — | — | US | disclosed |