Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.38 |
| ▸ | WNT3A | P56704 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366232 | 0.92 | ERN1 (0.48) | PGRERN1LMNAHPGDALDH1A1 | |
| SCHEMBL10600748 | 0.83 | LMNA (0.58) | ERN1LMNAHPGDCTNNB1WNT3A | |
| SCHEMBL10957588 | 0.76 | PGR (0.45) | PGRCTNNB1WNT3AALDH1A1KDM4E | |
| Acetic Acid SCHEMBL10957591 | 0.76 | PGR (0.45) | PGRCTNNB1WNT3AKDM4E | |
| SCHEMBL10597541 | 0.75 | ERN1 (0.52) | ERN1CTNNB1WNT3ACLK1DYRK1A | |
| SCHEMBL10915337 | 0.74 | ALDH1A1 (0.45) | ERN1LMNAHPGDCTNNB1WNT3A | |
| SCHEMBL5722689 | 0.74 | LMNA (0.61) | ERN1LMNAHPGDALDH1A1GAA | |
| SCHEMBL29190757 | 0.74 | KDM4E (0.50) | ERN1HPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6934978 | 0.73 | PGR (0.52) | PGRHPGDCTNNB1WNT3AALDH1A1 | |
| SCHEMBL17822006 | 0.72 | ERN1 (0.42) | ERN1CTNNB1WNT3AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558067-A | Phenylthiomethyl-6-hydroxy-2,3-dihydrobenzo-pyran and analogs thereof useful as anti-inflammatory agents | MERCK & CO., INC. (US) | 1985-12-10 | — | — | US | disclosed |