Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10960714 | 0.77 | PRMT6 (0.41) | L3MBTL1PRMT6 | |
| SCHEMBL1787840 | 0.73 | — | — | |
| SCHEMBL1085003 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL4485250 | 0.71 | POLB (0.42) | POLBTHRB | |
| Hydrochloric Acid SCHEMBL15464406 | 0.70 | — | — | |
| SCHEMBL19188713 | 0.68 | MAPT (0.44) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10865243 | 0.65 | NPC1 (0.34) | — | |
| SCHEMBL762438 | 0.65 | — | — | |
| SCHEMBL10960147 | 0.64 | L3MBTL1 (0.37) | L3MBTL1PRMT6CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15219435 | 0.63 | RAB9A (0.47) | L3MBTL1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4510309-A | ANTISECRETORY AND ANTIULCER AGENTS | BRISTOL-MYERS COMPANY (US) | 1985-04-09 | — | — | US | disclosed |
| US-4471122-A | Thiadiazole histamine H2 -antagonists | BRISTOL-MYERS COMPANY (US) | 1984-09-11 | — | — | US | disclosed |
| EP-0099121-A2 | Pharmaceutical compositions | Bristol-Myers Company (US) | 1984-01-25 | — | — | EP | disclosed |
| US-4394508-A | ANTIULCER AND ANTISECRETORY AGENTS; HISTAMINE ANTAGONIST | BRISTOL-MYERS COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| US-4380639-A | ANTIULCER AND ANTISECRETORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4380638-A | ANTIULCER AND ANTISECRETORY AGENTS; DERIVATIVES OF 3-AMINO-4-HET-A | BRISTOL-MYERS COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4374248-A | ANTIHISTAMINES, ANTIULCER | BRISTOL-MYERS COMPANY (US) | 1983-02-15 | — | — | US | disclosed |