Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12024356 | 0.77 | POLB (0.40) | POLBALDH1A1 | |
| SCHEMBL5848639 | 0.75 | ALDH1A1 (0.46) | POLBALDH1A1GAAMAPTKDM4E | |
| SCHEMBL12934633 | 0.72 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL10781847 | 0.68 | ALDH1A1 (0.50) | POLBALDH1A1GAAMAPTKDM4E | |
| SCHEMBL1095543 | 0.64 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL1095855 | 0.64 | CYP3A4 (0.39) | — | |
| SCHEMBL20000075 | 0.64 | ALDH1A1 (0.32) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL25021769 | 0.62 | ALDH1A1 (0.31) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL9446332 | 0.62 | ALDH1A1 (0.31) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL6842711 | 0.61 | ERN1 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107830-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | PURDUE RESEARCH FOUNDATION | 2012-05-03 | — | — | US | disclosed |
| US-8153827-B2 | Reagents for biomolecular labeling, detection and quantification employing Raman spectroscopy | PURDUE RESEARCH FOUNDATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-20090219526-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107830-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | SRMS, UQCRB, UQCRC1 | POLB 648/4885ALDH1A1 1681/4885GAA 2967/4885 |
| US-20090219526-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | SRMS, UQCRB, UQCRC1 | POLB 748/4885ALDH1A1 1294/4885GAA 2898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.