Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FHIT | P49789 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417041 | 0.78 | ALDH1A1 (0.44) | LMNATSHRKDM4EGAAPOLB | |
| SCHEMBL31296900 | 0.71 | LMNA (0.50) | LMNATSHRKDM4EGAAPOLB | |
| SCHEMBL11008658 | 0.71 | ALDH1A1 (0.62) | LMNATSHRKDM4EGAAALDH1A1 | |
| SCHEMBL5429764 | 0.68 | LMNA (0.47) | LMNATSHRKDM4EGAAPOLB | |
| SCHEMBL2328254 | 0.68 | LMNA (0.47) | LMNATSHRKDM4EGAAPOLB | |
| SCHEMBL10444735 | 0.67 | ALDH1A1 (0.58) | TSHRKDM4EGAAPOLBALDH1A1 | |
| SCHEMBL9397467 | 0.67 | ALDH1A1 (0.58) | TSHRGAAPOLBALDH1A1HPGD | |
| SCHEMBL31303968 | 0.67 | KDM4E (0.46) | LMNATSHRKDM4EGAAPOLB | |
| SCHEMBL31376339 | 0.67 | KDM4E (0.46) | LMNATSHRKDM4EGAAPOLB | |
| SCHEMBL3503405 | 0.67 | KDM4E (1.00) | LMNATSHRKDM4EGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552883-A | CNS DEPRESSANTS, ANXIOLYTICS | ICI AMERICAS INC. (US) | 1985-11-12 | — | — | US | disclosed |