SCHEMBL31376339

SCHEMBL31376339

CCOC(=O)C1=C(C(=O)OCC)C2C=CC1O2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.46
LMNA P02545 3/20 0.46
TSHR P16473 3/20 0.45
GAA P10253 3/20 0.43
POLB P06746 2/20 0.43
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA7 P43166 3/20 0.42
CA9 Q16790 3/20 0.42
CA14 Q9ULX7 3/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
ALDH1A1 P00352 3/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CYP1A2 P05177 3/20 0.41
CYP3A4 P08684 2/20 0.41
NR1H2 P55055 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19543295 0.93 ADORA3 (0.47) KDM4ELMNATSHRGAAPOLB
SCHEMBL19543293 0.90 KDM4E (0.42) KDM4ELMNATSHRGAAPOLB
SCHEMBL17266645 0.87 KDM4E (0.41) KDM4ELMNATSHRGAAPOLB
SCHEMBL4739182 0.83 HDAC4 (0.41) KDM4ELMNATSHRGAAPOLB
SCHEMBL12286065 0.83 ALDH1A1 (0.47) KDM4ETSHRGAAPOLBALDH1A1
SCHEMBL12286327 0.82 MAPT (0.43) LMNATSHRPOLBALDH1A1HPGD
SCHEMBL19543294 0.74 TSHR (0.38) KDM4ELMNATSHRGAAPOLB
SCHEMBL11582658 0.71 LMNA (0.46) KDM4ELMNATSHRGAAPOLB
SCHEMBL27647420 0.69 CA1 (0.79) LMNATSHRCA12CA1CA2
SCHEMBL10960435 0.67 LMNA (0.50) KDM4ELMNATSHRGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143774-A Selective hydrogenation method for substituted bicyclo [2.2.1] hepta-2, 5-diene 中国科学院大连化学物理研究所 2024-12-17 CN disclosed