Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.62 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.49 |
| ▸ | FDPS | P14324 | 4/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645181 | 0.79 | LAP3 (0.57) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL6552213 | 0.79 | LAP3 (0.72) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL15876022 | 0.77 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL745344 | 0.77 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL5690430 | 0.77 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL1060233 | 0.77 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL5691911 | 0.77 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL1059770 | 0.77 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL5691588 | 0.77 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL9307335 | 0.77 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063896-B1 | AMINO AND SUBSTITUTED AMINO PHOSPHINYL-ALKANOYL COMPOSITIONS | E.R. Squibb & Sons, Inc. (US) | 1985-08-14 | — | — | EP | disclosed |
| US-4416831-A | ANGIOTENSIN INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4374131-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1983-02-15 | — | — | US | disclosed |
| EP-0063896-A1 | Amino and substituted amino phosphinyl-alkanoyl compositions | E.R. Squibb & Sons, Inc. (US) | 1982-11-03 | — | — | EP | disclosed |