Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 6/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.53 |
| ▸ | ANPEP | P15144 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697329 | 0.88 | GRIK1 (0.55) | LAP3GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL9647092 | 0.86 | CA2 (0.55) | LAP3GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL9647060 | 0.83 | METAP1 (0.46) | LAP3GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL9647001 | 0.82 | LAP3 (0.72) | LAP3GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL9646181 | 0.82 | ALDH1A1 (0.46) | LAP3GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL9714012 | 0.82 | FOLH1 (0.62) | LAP3GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL15068278 | 0.82 | FOLH1 (0.62) | LAP3GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL9714134 | 0.82 | FOLH1 (0.62) | LAP3GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL9697381 | 0.81 | SLC1A2 (0.53) | LAP3GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL11112382 | 0.80 | GRIK1 (0.56) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | claimed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | claimed |
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5145990-A | Dehydropeptidase, carbapenicillin potentiation | MERCK & CO., INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-4962097-A | IN COMBINATION WITH A CARBAPENEM OR PENEM ANTIBIOTIC | MERCK & CO., INC. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | disclosed |