Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.52 |
| ▸ | ITGAL | P20701 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 5/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 4/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3730185 | 0.74 | — | — | |
| SCHEMBL38652945 | 0.74 | — | — | |
| SCHEMBL15610164 | 0.74 | ALDH1A1 (0.44) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL13369738 | 0.74 | ALDH1A1 (0.44) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL24107983 | 0.71 | ITGB1 (0.55) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL9312522 | 0.70 | ITGB1 (0.53) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL11212045 | 0.69 | — | — | |
| SCHEMBL11032630 | 0.69 | — | — | |
| SCHEMBL14559641 | 0.68 | SLC6A12 (0.46) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL10151005 | 0.67 | MAP3K14 (0.38) | ITGB1ITGA5ITGB3ITGB2ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151541-A2 | Saturated bicyclic lactam acids, their derivatives, a process for preparing the compounds and a pharmaceutical composition comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-14 | — | — | EP | disclosed |