Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 13/20 | 0.42 |
| ▸ | CA9 | Q16790 | 11/20 | 0.42 |
| ▸ | CA12 | O43570 | 11/20 | 0.42 |
| ▸ | CA7 | P43166 | 7/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 7/20 | 0.42 |
| ▸ | CA3 | P07451 | 6/20 | 0.42 |
| ▸ | CA6 | P23280 | 6/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.42 |
| ▸ | CA5A | P35218 | 5/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555157 | 0.85 | CISD1 (0.48) | CA2CA4CISD1CA1CA9 | |
| SCHEMBL10968089 | 0.85 | ALDH1A1 (0.48) | CA2CA4CISD1CA1CA9 | |
| SCHEMBL11705514 | 0.81 | CISD1 (0.67) | CA2CA4CISD1CA1CA9 | |
| SCHEMBL11104031 | 0.78 | CA12 (0.48) | CA2CA4CISD1CA1CA9 | |
| SCHEMBL11555741 | 0.76 | P2RX4 (0.46) | CA2CA4CA1CA9CA12 | |
| SCHEMBL10966139 | 0.76 | CA2 (0.46) | CA2CA4CISD1CA1CA9 | |
| SCHEMBL11710582 | 0.75 | CISD1 (0.58) | CA2CA4CISD1CA1CA9 | |
| SCHEMBL11709830 | 0.73 | CISD1 (0.62) | CA2CA4CISD1CA1CA9 | |
| Sulosemide SCHEMBL30704848 | 0.73 | ALDH1A1 (0.51) | CA2CA4CISD1CA1CA9 | |
| SCHEMBL11556930 | 0.73 | CISD1 (0.51) | CA2CA4CISD1CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047973-B1 | PROCESS FOR THE PRODUCTION OF 5-SULFAMOYL-ORTHANILIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-05 | — | — | EP | disclosed |
| EP-0047973-A1 | Process for the production of 5-sulfamoyl-orthanilic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-24 | — | — | EP | disclosed |