Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556930 | 0.89 | CISD1 (0.51) | CISD1PDE4DPDE3AP2RX4POLB | |
| SCHEMBL10964633 | 0.85 | CA2 (0.44) | CISD1P2RX4KDM4ETSHRCA2 | |
| SCHEMBL11708093 | 0.84 | CISD1 (0.69) | CISD1PDE4DPDE3AP2RX4POLB | |
| SCHEMBL11223169 | 0.82 | CISD1 (0.46) | CISD1PDE4DPDE3APOLBPTGS2 | |
| SCHEMBL10968089 | 0.82 | ALDH1A1 (0.48) | CISD1P2RX4POLBKDM4EL3MBTL1 | |
| SCHEMBL11098356 | 0.81 | CISD1 (0.43) | CISD1PDE4DPDE3APOLBPTGS2 | |
| SCHEMBL11215820 | 0.80 | CISD1 (0.43) | CISD1PDE4DPDE3APOLBPTGS2 | |
| SCHEMBL11554943 | 0.80 | CISD1 (0.46) | CISD1PDE4DPDE3AP2RX4POLB | |
| SCHEMBL11555741 | 0.71 | P2RX4 (0.46) | P2RX4SMN1; SMN2CA2TDP1CA4 | |
| Sulosemide SCHEMBL30704848 | 0.70 | ALDH1A1 (0.51) | CISD1P2RX4POLBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161533-A | DIURETICS, SALURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-17 | — | — | US | disclosed |