SCHEMBL109648

SCHEMBL109648

CC(C)COc1ccc(N)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.64
TSHR P16473 3/20 0.58
ALDH1A1 P00352 6/20 0.55
GAA P10253 2/20 0.55
MAPT P10636 5/20 0.49
KDM4E B2RXH2 3/20 0.49
NPSR1 Q6W5P4 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
LMNA P02545 2/20 0.49
HPGD P15428 3/20 0.47
POLB P06746 2/20 0.47
XBP1 P17861 1/20 0.47
XDH P47989 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MAOA P21397 2/20 0.45
MAOB P27338 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL738082 0.98 TDP1 (0.62) TDP1TSHRALDH1A1GAAMAPT
SCHEMBL123415 0.88 MAPT (0.55) TDP1TSHRALDH1A1MAPTKDM4E
SCHEMBL14407437 0.86 TDP1 (0.59) TDP1TSHRALDH1A1GAAMAPT
SCHEMBL6912197 0.83 LMNA (0.64) TDP1TSHRALDH1A1GAAMAPT
SCHEMBL9906017 0.82 KMT2A (0.50) TDP1TSHRALDH1A1MAPTKDM4E
SCHEMBL20851318 0.81 MAPT (0.58) TSHRALDH1A1GAAMAPTKDM4E
SCHEMBL10870781 0.81 TDP1 (0.53) TDP1TSHRALDH1A1GAAMAPT
SCHEMBL8896344 0.81 TDP1 (0.53) TDP1TSHRALDH1A1GAAMAPT
SCHEMBL11272090 0.81 TDP1 (0.53) TDP1TSHRALDH1A1GAAMAPT
SCHEMBL11157593 0.79 TAAR1 (0.57) LMNAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102911972-B Preparation method of algistatic active substance di-isobutoxyphenyl amine UNIV XIAMEN 2015-01-21 CN claimed
CN-102911972-A Preparation method of algistatic active substance di-isobutoxyphenyl amine UNIV XIAMEN 2013-02-06 CN claimed
US-6107487-A FREE OF WATER-SOLUBILIZING GROUPS; SUITABLE FOR THERMAL DYE TRANSFER AND FOR DYEING AND PRINTING SYNTHETIC MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2000-08-22 US claimed
EP-4724443-A1 PYRAZOLO-PYRIMIDINONE COMPOUNDS FOR USE IN METHODS OF INHIBITING WEE1 A KINASE Acrivon Therapeutics, Inc. (US) 2026-04-15 EP disclosed
WO-2024254490-A1 PYRAZOLO-PYRIMIDINONE COMPOUNDS FOR USE IN METHODS OF INHIBITING WEE1 A KINASE ACRIVON THERAPEUTICS, INC. (US) 2024-12-12 WO disclosed
US-20240246920-A1 TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY KING'S COLLEGE LONDON (GB) 2024-07-25 US disclosed
WO-2024043285-A1 RESIN COMPOSITION, COMPOSITE REINFORCING MATERIAL, MOLDED BODY, AND METHOD FOR RECOVERING REINFORCING FIBERS FROM COMPOSITE REINFORCING MATERIAL 旭化成株式会社 2024-02-29 WO disclosed
EP-4100400-A1 TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY Kings College London (GB) 2022-12-14 EP disclosed
CN-114716707-A Polyimide film, copper sheet laminated plate, and circuit board 日铁化学材料株式会社 2022-07-08 CN disclosed
WO-2021156636-A1 TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY KING'S COLLEGE LONDON (GB) 2021-08-12 WO disclosed
CN-111423333-B Diamine monomer containing heptaphenyltriamine-double fluorophore structure, preparation and application thereof, polyamide and polyimide, and preparation and application thereof 吉林大学 2021-02-12 CN disclosed
US-5373023-A Antiischaemic agent SYNTHELABO (FR) 1994-12-13 US disclosed
EP-0582506-A1 Tetrahydronaphtalene derivatives, their preparation and their application in therapy SYNTHELABO (FR) 1994-02-09 EP disclosed
EP-0207350-B1 PROCESS FOR PREPARING DIARYL SULPHIDES CASSELLA Aktiengesellschaft (DE) 1989-01-18 EP disclosed
US-4686303-A Process for the preparation of diaryl sulphides CASSELLA AKTIENGESELLSCHAFT (DE) 1987-08-11 US disclosed
EP-0207350-A1 Process for preparing diaryl sulphides CASSELLA Aktiengesellschaft (DE) 1987-01-07 EP disclosed
EP-0039312-B1 COLOUR PHOTOPGRAPHIC MATERIAL FOR THE SILVER-DYE BLEACHING PROCESS, PROCESS FOR THE PRODUCTION OF THIS MATERIAL AND ITS USE IN THE PRODUCTION OF PHOTOGRAPHIC IMAGES CIBA-GEIGY AG (CH) 1983-12-28 EP disclosed
US-4379819-A OIL SOLUBLE MONOAZO DYE CIBA-GEIGY AG (CH) 1983-04-12 US disclosed
EP-0056475-A2 Pharmaceutical compositions MERCK PATENT GmbH (DE) 1982-07-28 EP disclosed
EP-0039312-A1 Colour photopgraphic material for the silver-dye bleaching process, process for the production of this material and its use in the production of photographic images CIBA-GEIGY AG (CH) 1981-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240246920-A1 TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY RIF1, NAT1, POLR1C TDP1 1308/4885TSHR 2628/4885ALDH1A1 381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.