Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HTR1F | P30939 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215489 | 0.88 | HTR1F (0.61) | MGLLHSD11B1MEN1KMT2AHTR1F | |
| SCHEMBL5208639 | 0.87 | HTR1F (0.73) | MEN1KMT2AHTR1FPOLB | |
| SCHEMBL6183451 | 0.87 | ALDH1A1 (0.61) | MGLLHSD11B1MEN1KMT2AALDH1A1 | |
| SCHEMBL5210817 | 0.86 | HTR1F (0.65) | KMT2AHTR1F | |
| SCHEMBL16447329 | 0.85 | MGLL (0.64) | MGLLHSD11B1MEN1KMT2AALDH1A1 | |
| SCHEMBL5212220 | 0.84 | MGLL (0.63) | MGLLHTR1F | |
| SCHEMBL5210802 | 0.84 | HTR1F (0.46) | MGLLHSD11B1MEN1KMT2AHTR1F | |
| SCHEMBL5210311 | 0.84 | HTR1F (0.62) | MEN1KMT2AHTR1FALDH1A1NPSR1 | |
| SCHEMBL4223027 | 0.83 | HTR1F (0.55) | MGLLMEN1KMT2AHTR1FALDH1A1 | |
| SCHEMBL4223030 | 0.83 | MGLL (0.59) | MGLLHSD11B1MEN1KMT2AHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408323-B | Piperidines urea derivative | 默克专利股份公司 | 2018-03-13 | — | — | CN | disclosed |
| EP-0037265-B1 | 3-(1-PIPERIDINYLALKYL)-4H-PYRIDO(1,2-A)PYRIMIDIN-4-ONE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-01-23 | — | — | EP | disclosed |
| EP-0013612-B1 | (PIPERIDINYLALKYL)QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-11-09 | — | — | EP | disclosed |