Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139928 | 1.00 | KDM4E (0.34) | KDM4EMAPK1CASP1HSD17B10ALDH1A1 | |
| SCHEMBL10625245 | 0.73 | HDAC1 (0.36) | ALDH1A1HDAC1 | |
| SCHEMBL10625247 | 0.73 | HDAC1 (0.36) | ALDH1A1HDAC1 | |
| SCHEMBL1176177 | 0.71 | ALDH1A1 (0.31) | HSD17B10ALDH1A1 | |
| SCHEMBL10576019 | 0.70 | SMN1; SMN2 (0.37) | KDM4EMAPK1ALDH1A1GAARAB9A | |
| SCHEMBL8403668 | 0.69 | — | — | |
| SCHEMBL10625236 | 0.68 | LMNA (0.39) | MAPK1HSD17B10 | |
| SCHEMBL10625235 | 0.68 | LMNA (0.39) | MAPK1HSD17B10 | |
| SCHEMBL6301510 | 0.68 | IDO1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL10915486 | 0.68 | GAA (0.44) | KDM4EHSD17B10ALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036387-B1 | PROCESS FOR THE PREPARATION OF HYDRAZONO-ISOINDOLINES | CIBA-GEIGY AG (CH) | 1986-01-22 | — | — | EP | disclosed |
| US-4414395-A | REACTING AN IMINOISOINDOLE WITH HYDRAZINE | CIBA-GEIGY CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0036387-A2 | Process for the preparation of hydrazono-isoindolines | CIBA-GEIGY AG (CH) | 1981-09-23 | — | — | EP | disclosed |