SCHEMBL6301510

SCHEMBL6301510

N#CC(=O)NC=C1NC(=N)c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.35
MAPK10 P53779 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10625247 0.73 HDAC1 (0.36) ALDH1A1MAPTCYP1A2CYP3A4CYP2C9
SCHEMBL10625245 0.73 HDAC1 (0.36) ALDH1A1MAPTCYP1A2CYP3A4CYP2C9
SCHEMBL10625236 0.71 LMNA (0.39) MAPTSMN1; SMN2HPGD
SCHEMBL10625235 0.71 LMNA (0.39) MAPTSMN1; SMN2HPGD
SCHEMBL11810458 0.70
SCHEMBL1176177 0.69 ALDH1A1 (0.31) IDO1ALDH1A1MAPTSMN1; SMN2
SCHEMBL10915486 0.68 GAA (0.44) KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL3139928 0.68 KDM4E (0.34) KDM4EALDH1A1
SCHEMBL10965716 0.68 KDM4E (0.34) KDM4EALDH1A1
SCHEMBL11270482 0.68 CYP1A2 (0.32) CYP1A2CYP3A4CYP2C9HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5134189-A Isocyanate, Imino Compound, Polymeric Binder MITSUBISHI PAPER MILLS LIMITED (JP) 1992-07-28 US claimed
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed
US-6232266-B1 COMPRISES TWO OR MORE KINDS OF COMPOUNDS, AND AT LEAST ONE OF WHICH IS FORMED A COLOR-FORMATION CONTROLLING LAYER OBTAINED BY POLYMERIZING A COMPOUND HAVING AN UNSATURATED CARBON BOND. MITSUBISHI PAPER MILLS LIMITED (JP) 2001-05-15 US disclosed
EP-0427929-B1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1995-11-02 EP disclosed
EP-0439638-B1 Heat sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1995-06-14 EP disclosed
US-5246905-A Aromatic isocyanate, imino compound, fluoran dye MITSUBISHI PAPER MILLS LIMITED (JP) 1993-09-21 US disclosed
US-5134189-A Isocyanate, Imino Compound, Polymeric Binder MITSUBISHI PAPER MILLS LIMITED (JP) 1992-07-28 US disclosed
US-5098738-A Coating a suspension of an isocyanate and an imino compound for color development and adjustment of pH with acid or base ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1992-03-24 US disclosed
US-5098881-A A support with an aromatic isocyanate that reacts with an amine to form color and a metallic soap MITSUBISHI PAPER MILLS LTD. (JP) 1992-03-24 US disclosed
US-5093305-A Phenolic Compound, Aromatic Isocyanate, Imine MITSUBISHI PAPER MILLS LIMITED (JP) 1992-03-03 US disclosed
US-5036039-A Aromatic isocyanate and imine MITSUBISHI PAPER MILLS LIMITED (JP) 1991-07-30 US disclosed
EP-0427929-A2 Heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1991-05-22 EP disclosed
US-4983569-A Color-forming layer comprising a fluorene dye chromogen, a developer, an isocyanate and an imino compound; infrared absorption; storage stability; colorfastness MITSUBISHI PAPER MILLS (JP) 1991-01-08 US disclosed
US-4965237-A AROMATICITY-POSESSING ISOCYANATE COMPOUND, IMINO COMPOUND, AND ANILINE DERIVATIVE MITSUBISHI PAPER MILLS, LTD. (JP) 1990-10-23 US disclosed
US-4880767-A COLOR FORMING SYSTEMS, FLUORENE DYES, DYE DEVELOPERS MITSUBISHI PAPER MILLS (JP) 1989-11-14 US disclosed
EP-0101741-B1 COLORING METHOD AND COLOR-FORMING MATERIAL Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-05-20 EP disclosed
US-4521793-A Coloring method and color-forming material ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-06-04 US disclosed
EP-0101741-A1 COLORING METHOD AND COLOR-FORMING MATERIAL Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-03-07 EP disclosed
US-4356123-A YELLOW PIGMENT BASF AKTIENGESELLSCHAFT (DE) 1982-10-26 US disclosed
US-3991054-A FOR POLYESTERS BASF AKTIENGESELLSCHAFT (DT) 1976-11-09 US disclosed