Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 10/20 | 0.71 |
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253839 | 0.89 | ICMT (0.69) | ICMTCDC25APLA2G2ACNR2MCL1 | |
| SCHEMBL2465449 | 0.88 | CDC25A (0.68) | ICMTCDC25AHTR6MCL1 | |
| SCHEMBL4988587 | 0.87 | ICMT (0.74) | ICMTCDC25APLA2G2ACNR2MCL1 | |
| SCHEMBL27446555 | 0.85 | ICMT (0.64) | ICMTCDC25APLA2G2AHTR6MCL1 | |
| SCHEMBL2595601 | 0.84 | ICMT (0.71) | ICMTCDC25APLA2G2A | |
| SCHEMBL3667313 | 0.84 | ICMT (0.97) | ICMTCDC25A | |
| SCHEMBL11893393 | 0.83 | ICMT (1.00) | ICMTCDC25A | |
| SCHEMBL13241404 | 0.82 | ICMT (0.67) | ICMTCDC25APLA2G2ACNR2MCL1 | |
| SCHEMBL8086295 | 0.82 | ICMT (0.71) | ICMTCDC25AHTR6CNR2 | |
| SCHEMBL8289938 | 0.82 | PLA2G2A (0.74) | ICMTPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035474-B1 | AMIDINES, PROCESS FOR THEIR PRODUCTION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |
| US-4444768-A | ICE CREAM CONE WRAPPER | CIBA-GEIGY CORPORATION (US) | 1984-04-24 | — | — | US | disclosed |
| EP-0035474-A1 | Amidines, process for their production, pharmaceutical preparations containing them and their use | CIBA-GEIGY AG (CH) | 1981-09-09 | — | — | EP | disclosed |