Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.37 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14628587 | 0.83 | TSHR (0.41) | TSHRFOLH1NAALAD2RIMKLAGABRP | |
| SCHEMBL25269853 | 0.83 | CA1 (0.49) | — | |
| SCHEMBL25269854 | 0.83 | CA1 (0.49) | — | |
| SCHEMBL11230702 | 0.81 | PLA2G2C (0.40) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL10963515 | 0.78 | EPHX1 (0.40) | — | |
| SCHEMBL11232274 | 0.75 | GABRP (0.47) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10968397 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL11227787 | 0.74 | HTT (0.52) | FOLH1 | |
| SCHEMBL14497656 | 0.73 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14597980 | 0.73 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046712-B1 | FLUORINATED DIAMINOBUTANE DERIVATIVES | MERRELL TORAUDE ET COMPAGNIE (FR) | 1985-02-06 | — | — | EP | disclosed |
| US-4435425-A | INHIBITORS OF GAMMA-AMINOBUTYRIC ACID TRANSAMINASE | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-03-06 | — | — | US | disclosed |
| EP-0046712-A1 | Fluorinated diaminobutane derivatives | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-03-03 | — | — | EP | disclosed |