Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 10/20 | 0.38 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10965852 | 0.83 | TSHR (0.39) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL14597980 | 0.74 | FOLH1 (0.64) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL14497656 | 0.74 | FOLH1 (0.64) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL25745387 | 0.74 | REN (0.41) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL31450785 | 0.73 | FOLH1 (0.47) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL21150988 | 0.73 | FOLH1 (0.47) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL18756332 | 0.72 | GABRP (0.45) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL28230319 | 0.72 | CTSK (0.45) | FOLH1 | |
| SCHEMBL27880264 | 0.72 | FOLH1 (0.37) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL25745409 | 0.72 | FOLH1 (0.44) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070009980-A1 | Continuous fluorogenic analyte assays with dendritic amplification of signal | APPLERA CORPORATION (US) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070009980-A1 | Continuous fluorogenic analyte assays with dendritic amplification of signal | CD69, FLT3, IRF3 | TSHR 1600/4885TET2 746/4885KDM4A 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.