Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881162 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8508358 | 0.86 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL10560416 | 0.84 | MAPT (0.44) | ALDH1A1SMN1; SMN2MAPTLMNACYP1A2 | |
| SCHEMBL10969382 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL733453 | 0.82 | MAPT (0.53) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL10840202 | 0.82 | MAPT (0.44) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL10880485 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL10981628 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL10981472 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL9420221 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046467-B1 | QUINOXALINE DERIVATIVES AND HERBICIDAL COMPOSITION | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-03-27 | — | — | EP | claimed |