Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | EDNRA | P25101 | 2/20 | 0.60 |
| ▸ | EDNRB | P24530 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844446 | 0.92 | ALDH1A1 (0.62) | ALDH1A1EDNRAEDNRBSMN1; SMN2MAPT | |
| SCHEMBL19337473 | 0.82 | ALDH1A1 (0.54) | ALDH1A1EDNRAEDNRBSMN1; SMN2MAPT | |
| SCHEMBL10846999 | 0.80 | CA1 (0.53) | ALDH1A1EDNRAEDNRBMAPTHPGD | |
| SCHEMBL10971038 | 0.80 | CA2 (0.53) | ALDH1A1EDNRAEDNRBHPGDCA4 | |
| SCHEMBL10843954 | 0.80 | SMN1; SMN2 (0.65) | ALDH1A1EDNRASMN1; SMN2MAPTTP53 | |
| SCHEMBL11585921 | 0.79 | LTA4H (0.52) | ALDH1A1SMN1; SMN2MAOALTA4HMAOB | |
| SCHEMBL16142360 | 0.79 | CA4 (0.59) | ALDH1A1EDNRAEDNRBSMN1; SMN2MAPT | |
| SCHEMBL23914088 | 0.77 | ALDH1A1 (0.52) | ALDH1A1EDNRAEDNRBSMN1; SMN2MAPT | |
| SCHEMBL10407256 | 0.77 | ALDH1A1 (0.56) | ALDH1A1EDNRAEDNRBSMN1; SMN2MAPT | |
| SCHEMBL23913947 | 0.77 | ALDH1A1 (0.52) | ALDH1A1EDNRAEDNRBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068880-B1 | PHOTOGRAPHIC ELEMENTS CAPABLE OF PROVIDING OXOINDOLIZINE AND OXOINDOLIZINIUM DYE COMPOUNDS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-08-07 | — | — | EP | claimed |
| US-4128422-A | Cyclopropenone vesicular imaging composition, element and process | EASTMAN KODAK COMPANY (US) | 1978-12-05 | — | — | US | claimed |
| EP-0068880-B1 | PHOTOGRAPHIC ELEMENTS CAPABLE OF PROVIDING OXOINDOLIZINE AND OXOINDOLIZINIUM DYE COMPOUNDS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4119466-A | MEROCYANINE DYES | EASTMAN KODAK COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4062686-A | MEROCYANINE BENZOTHIAZOLINES OR BENZOSELENAZOLINES | EASTMAN KODAK COMPANY (US) | 1977-12-13 | — | — | US | disclosed |