Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128860 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10963820 | 0.80 | TP53 (0.57) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11017212 | 0.80 | KDM4E (0.42) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11021464 | 0.79 | KEAP1 (0.42) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL439731 | 0.79 | LIG1 (0.56) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10339858 | 0.77 | KEAP1 (0.56) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2424940 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL11358929 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL11022685 | 0.76 | KDM4E (0.39) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11017927 | 0.76 | KDM4E (0.41) | KEAP1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106133984-A | Addition agent of non-aqueous electrolyte, nonaqueous electrolytic solution and electrical storage device | 住友精化株式会社 | 2016-11-16 | — | — | CN | disclosed |
| US-4556651-A | Secalonic acid derivatives as antitumor agents | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-12-03 | — | — | US | disclosed |
| EP-0064199-B1 | NOVEL SECALONIC ACID DERIVATIVES AND METHOD FOR PREPARING THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1985-08-21 | — | — | EP | disclosed |
| US-4418061-A | ANTITUMOR AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-11-29 | — | — | US | disclosed |
| EP-0064199-A1 | Novel secalonic acid derivatives and method for preparing thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-11-10 | — | — | EP | disclosed |