Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 3/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823345 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL543980 | 0.83 | MEN1 (0.55) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL5128860 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL11358929 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL70816 | 0.80 | TSHR (0.62) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL70284 | 0.80 | MAPT (0.67) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL69292 | 0.79 | MAPT (0.61) | ALDH1A1HSD17B10MAPTMEN1TSHR | |
| SCHEMBL439731 | 0.79 | LIG1 (0.56) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL11782331 | 0.78 | TSHR (0.59) | KDM4EALDH1A1HSD17B10MAPTTSHR | |
| SCHEMBL6760793 | 0.77 | MAPT (0.59) | ALDH1A1HSD17B10MAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013142093-A1 | METHOD FOR THE SYNTHESIS OF DROXIDOPA | CHELSEA THERAPEUTICS, INC. (US) | 2013-09-26 | — | — | WO | claimed |
| EP-2542527-A2 | PROCESS FOR THE PREPARATION OF ATAZANAVIR SULFATE SUBSTANTIALLY FREE OF DIASTEREOMERS | Lupin Limited (IN) | 2013-01-09 | — | — | EP | claimed |
| WO-2011107843-A2 | PROCESS FOR THE PREPARATION OF ATAZANAVIR SULFATE SUBSTANTIALLY FREE OF DIASTEREOMERS | LUPIN LIMITED (IN) | 2011-09-09 | — | — | WO | claimed |
| CN-106660032-A | Solid acid catalyst and method for producing oxide | 株式会社大赛璐 | 2017-05-10 | — | — | CN | disclosed |
| CN-106660910-A | OXIDATION REACTOR AND PROCESS FOR PRODUCING OXIDE | 公立大学法人大阪府立大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-106573858-A | Oxidation reactor and production method for oxide | 株式会社大赛璐 | 2017-04-19 | — | — | CN | disclosed |
| WO-2013142093-A1 | METHOD FOR THE SYNTHESIS OF DROXIDOPA | CHELSEA THERAPEUTICS, INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| US-4345071-A | AZIDOALKYL-HETEROCYCLIC AMIDINE INTERMEDIATES | LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) | 1982-08-17 | — | — | US | disclosed |
| US-4229443-A | Derivatives of penicillanic acid | LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) | 1980-10-21 | — | — | US | disclosed |