Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016793 | 0.82 | KEAP1 (0.39) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11020098 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11017212 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11021464 | 0.77 | KEAP1 (0.42) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11019205 | 0.77 | KDM4E (0.35) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL10967338 | 0.76 | KEAP1 (0.59) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| Bicarbonate SCHEMBL23581765 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11017187 | 0.73 | HSD17B10 (0.34) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL2156113 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL29212759 | 0.71 | KDM4E (0.49) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |