Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10968388 | 0.81 | MAPT (0.40) | LMNATP53MAPTMEN1NPC1 | |
| SCHEMBL8307891 | 0.70 | USP2 (0.40) | LMNAMEN1NPC1KMT2AGAA | |
| SCHEMBL4870707 | 0.69 | MAPT (0.51) | LMNAMAPTNPC1KMT2AGAA | |
| SCHEMBL11370116 | 0.66 | LMNA (0.75) | LMNATP53MAPTMEN1NPC1 | |
| SCHEMBL10922914 | 0.66 | MAPT (0.52) | LMNATP53MAPTMEN1NPC1 | |
| SCHEMBL10466265 | 0.65 | MAPT (0.49) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL14224873 | 0.65 | MAPT (0.38) | LMNATP53MAPTMEN1NPC1 | |
| SCHEMBL14197617 | 0.65 | MAPT (0.38) | LMNATP53MAPTMEN1NPC1 | |
| SCHEMBL16741154 | 0.65 | SMN1; SMN2 (0.46) | LMNAMAPTNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL9416788 | 0.65 | SMN1; SMN2 (0.59) | LMNAMAPTNPC1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075600-B1 | 2-THIAZOLEAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-12-30 | — | — | EP | disclosed |