Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304607 | 0.80 | GPR55 (0.42) | MAPK8MAPK9MAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8304605 | 0.80 | GPR55 (0.42) | MAPK8MAPK9MAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8302198 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1KDM4EMIFLMNA | |
| SCHEMBL8302035 | 0.71 | MIF (0.35) | SMN1; SMN2GAAKDM4ENPC1RAB9A | |
| SCHEMBL8302038 | 0.71 | MIF (0.35) | SMN1; SMN2GAAKDM4ENPC1RAB9A | |
| SCHEMBL10967407 | 0.70 | LMNA (0.49) | SMN1; SMN2ALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL580260 | 0.69 | MAPK8 (0.40) | USP2MAPK8MAPK9MAPK10SMN1; SMN2 | |
| SCHEMBL1479525 | 0.69 | MAPK8 (0.40) | USP2MAPK8MAPK9MAPK10SMN1; SMN2 | |
| SCHEMBL14036908 | 0.69 | RET (0.31) | ALDH1A1KDM4E | |
| SCHEMBL9803634 | 0.69 | GAA (0.44) | USP2MAPK8MAPK9MAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948485-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1999-10-13 | — | — | EP | claimed |
| WO-1998028278-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | claimed |