Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.36 |
| ▸ | BCHE | P06276 | 8/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10957232 | 0.77 | PRMT6 (0.59) | ACHEBCHEPRMT6 | |
| SCHEMBL11259371 | 0.67 | HRH2 (0.37) | ACHEBCHE | |
| SCHEMBL10959685 | 0.66 | PRMT6 (0.59) | ACHEBCHEPRMT6 | |
| SCHEMBL11310217 | 0.66 | ACHE (0.45) | ACHEBCHE | |
| SCHEMBL11254573 | 0.66 | ACHE (0.45) | ACHEBCHE | |
| SCHEMBL11248627 | 0.66 | KDM4E (0.41) | ACHEBCHE | |
| SCHEMBL10958506 | 0.65 | ACHE (0.40) | ACHEBCHE | |
| SCHEMBL11104799 | 0.63 | HRH2 (0.40) | ACHEBCHE | |
| SCHEMBL11252579 | 0.63 | PRMT6 (0.57) | ACHEBCHEPRMT6 | |
| SCHEMBL10750497 | 0.62 | HRH2 (0.35) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049049-B1 | 5-AMINO-TETRAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1985-11-13 | — | — | EP | disclosed |