Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 16/20 | 0.45 |
| ▸ | BCHE | P06276 | 10/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959685 | 0.88 | PRMT6 (0.59) | PRMT6ACHEBCHE | |
| SCHEMBL11252579 | 0.84 | PRMT6 (0.57) | PRMT6ACHEBCHE | |
| SCHEMBL11252584 | 0.81 | PRMT6 (0.55) | PRMT6ACHEBCHE | |
| SCHEMBL11254687 | 0.81 | PRMT6 (0.55) | PRMT6ACHEBCHEAPEX1 | |
| SCHEMBL11253283 | 0.79 | APEX1 (0.52) | PRMT6ACHEBCHEAPEX1 | |
| SCHEMBL11260097 | 0.79 | PRMT6 (0.52) | PRMT6ACHEBCHE | |
| SCHEMBL11244950 | 0.79 | PRMT6 (0.41) | PRMT6APEX1 | |
| SCHEMBL11460483 | 0.78 | PRMT6 (0.44) | PRMT6ACHEBCHE | |
| SCHEMBL10967495 | 0.77 | ACHE (0.36) | PRMT6ACHEBCHE | |
| SCHEMBL11479765 | 0.77 | PRMT6 (0.42) | PRMT6ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049049-B1 | 5-AMINO-TETRAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1985-11-13 | — | — | EP | disclosed |
| US-4536508-A | ANTIALLERGENS AND ANTIINFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 1985-08-20 | — | — | US | disclosed |
| US-4510309-A | ANTISECRETORY AND ANTIULCER AGENTS | BRISTOL-MYERS COMPANY (US) | 1985-04-09 | — | — | US | disclosed |
| US-4471122-A | Thiadiazole histamine H2 -antagonists | BRISTOL-MYERS COMPANY (US) | 1984-09-11 | — | — | US | disclosed |
| EP-0016565-B1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |
| US-4394508-A | ANTIULCER AND ANTISECRETORY AGENTS; HISTAMINE ANTAGONIST | BRISTOL-MYERS COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| US-4380639-A | ANTIULCER AND ANTISECRETORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4380638-A | ANTIULCER AND ANTISECRETORY AGENTS; DERIVATIVES OF 3-AMINO-4-HET-A | BRISTOL-MYERS COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4374248-A | ANTIHISTAMINES, ANTIULCER | BRISTOL-MYERS COMPANY (US) | 1983-02-15 | — | — | US | disclosed |
| EP-0049049-A1 | 5-Amino-tetrazole derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1982-04-07 | — | — | EP | disclosed |
| EP-0001699-B1 | DERIVATIVES OF FURYL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1982-02-24 | — | — | EP | disclosed |
| US-4288443-A | HISTAMINE ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1981-09-08 | — | — | US | disclosed |
| EP-0016565-A1 | 1,2,4-Triazole derivatives, processes for their production and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1980-10-01 | — | — | EP | disclosed |
| EP-0001699-A2 | Derivatives of furyl compounds, their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1979-05-02 | — | — | EP | disclosed |