Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677819 | 0.80 | ALDH1A1 (0.43) | GAAALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27631985 | 0.74 | ALDH1A1 (0.52) | GAAALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL10677212 | 0.74 | NPC1 (0.34) | GAANPC1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL10672830 | 0.72 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL10967638 | 0.72 | BCL9 (0.51) | BCL9CTNNB1GAANPC1ALDH1A1 | |
| SCHEMBL10682274 | 0.71 | NPC1 (0.35) | BCL9CTNNB1GAANPC1ALDH1A1 | |
| SCHEMBL10678819 | 0.71 | ALDH1A1 (0.55) | GAANPC1ALDH1A1KMT2ALMNA | |
| SCHEMBL10673376 | 0.70 | DAGLA (0.33) | ALDH1A1 | |
| SCHEMBL10676665 | 0.70 | MEN1 (0.34) | ALDH1A1KMT2AMAPK1 | |
| SCHEMBL7823769 | 0.70 | POLB (0.49) | NPC1ALDH1A1KMT2ATSHRKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035046-B1 | NOVEL TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |
| EP-0035046-A1 | Novel tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-09 | — | — | EP | disclosed |