Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23537838 | 0.80 | LMNA (0.53) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL7823769 | 0.78 | POLB (0.49) | ALDH1A1KMT2ALMNACYP19A1MAPT | |
| SCHEMBL24455248 | 0.77 | PKM (0.64) | ALDH1A1KMT2ALMNASYKMAOB | |
| SCHEMBL19288490 | 0.77 | SYK (0.50) | ALDH1A1KMT2AKDM4ELMNASYK | |
| SCHEMBL5654058 | 0.75 | CYP1A2 (0.45) | ALDH1A1KMT2AKDM4ELMNAIDO1 | |
| SCHEMBL11755910 | 0.75 | LMNA (0.58) | ALDH1A1KMT2AGAAKDM4ELMNA | |
| SCHEMBL10967641 | 0.74 | BCL9 (0.44) | ALDH1A1KMT2AGAAKDM4ELMNA | |
| SCHEMBL3097893 | 0.71 | FFAR1 (0.51) | ALDH1A1KMT2AGAALMNAIDO1 | |
| SCHEMBL7348258 | 0.71 | LMNA (0.58) | LMNAMAOBMAPTCA12CA1 | |
| SCHEMBL11756075 | 0.70 | LMNA (0.51) | ALDH1A1KMT2AGAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |