SCHEMBL10967696

SCHEMBL10967696

CCOC(=O)/C(=N/c1cc(Cl)cc(Cl)c1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.53
ALDH1A1 P00352 5/20 0.49
MAPT P10636 3/20 0.49
LMNA P02545 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
CYP19A1 P11511 1/20 0.42
ABCB1 P08183 1/20 0.41
GAA P10253 1/20 0.40
CASP1 P29466 1/20 0.40
ATM Q13315 2/20 0.40
TSHR P16473 1/20 0.40
NPC1 O15118 2/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10965996 1.00 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1MAPTLMNATDP1
SCHEMBL10966244 0.84 TSHR (0.41) SMN1; SMN2ALDH1A1MAPTLMNATDP1
SCHEMBL11418652 0.81 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1MAPTLMNAKMT2A
SCHEMBL11423946 0.81 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL11416902 0.80 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1MAPTLMNATDP1
SCHEMBL10965966 0.79 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1MAPTLMNATDP1
SCHEMBL10965962 0.79 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1MAPTLMNATDP1
SCHEMBL11416431 0.79 SMN1; SMN2 (0.55) SMN1; SMN2ALDH1A1MAPTLMNATDP1
SCHEMBL11418654 0.75 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1MAPTLMNATDP1
SCHEMBL11417709 0.74 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1MAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0097107-B1 PHENYLIMINO-2-ACETIC-ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE IN REGULATING THE GROWTH OF PLANTS RHONE-POULENC AGROCHIMIE (FR) 1985-09-18 EP claimed