Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11409704 | 0.86 | CRHR1 (0.49) | SMN1; SMN2MAPTCRHR1HTR3EHTR3B | |
| SCHEMBL11418652 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2CES2ACHECES1ALDH1A1 | |
| SCHEMBL11416362 | 0.82 | HTR3E (0.51) | SMN1; SMN2MAPTCRHR1HTR3EHTR3B | |
| SCHEMBL10967696 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10965996 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11418654 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27346857 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2CES2ACHECES1ALDH1A1 | |
| SCHEMBL11417709 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2ACHEALDH1A1MAPTMEN1 | |
| SCHEMBL11415317 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2CES2ACHECES1ALDH1A1 | |
| SCHEMBL11416431 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1MAPTHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230727-A | N-BENZYLIDENEANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1980-10-28 | — | — | US | disclosed |