Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404995 | 0.84 | RAB9A (0.46) | SMN1; SMN2ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL11423946 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL11423274 | 0.82 | PRSS1 (0.48) | SMN1; SMN2ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL10967696 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL10965996 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL11411115 | 0.80 | CES2 (0.52) | SMN1; SMN2ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL11418654 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL11417709 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL9611218 | 0.77 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL11415317 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200648-A | INFLAMMATION BY ADMINISTERING A BENZYLIDENEANILINE DERIVATIVE | WILLIAM H. RORER, INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |