Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 5/20 | 0.39 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777788 | 0.76 | LMNA (0.44) | LMNAHTR2AHRH1TAAR1SLC6A3 | |
| SCHEMBL12774635 | 0.76 | SLC6A3 (0.56) | LMNAHTR2AHRH1TAAR1SLC6A3 | |
| SCHEMBL1615641 | 0.76 | EPHX1 (0.40) | SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12128404 | 0.74 | KMT2A (0.44) | LMNAHTR2AHRH1TAAR1SLC6A3 | |
| SCHEMBL8693156 | 0.74 | CYP1A2 (0.39) | LMNAHTR2ATAAR1SLC6A3CYP1A2 | |
| SCHEMBL1758751 | 0.74 | CYP2C19 (0.40) | HTR2AHRH1TAAR1SLC6A3CYP1A2 | |
| SCHEMBL9681031 | 0.73 | TAAR1 (0.41) | LMNAHTR2AHRH1MIFTAAR1 | |
| SCHEMBL19485917 | 0.73 | DPP4 (0.44) | LMNAHTR2ATAAR1SLC6A3CYP1A2 | |
| SCHEMBL12381822 | 0.73 | LMNA (0.46) | LMNAHTR2AHRH1MIFTAAR1 | |
| SCHEMBL14515481 | 0.70 | LMNA (0.43) | LMNASLC6A3CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055444-B1 | TRISUBSTITUTED PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-03-20 | — | — | EP | claimed |
| EP-0055444-B1 | TRISUBSTITUTED PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |
| US-4478833-A | ANTICOAGULANTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |