Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956655 | 0.75 | TSHR (0.46) | TAAR1TDP1HTR2AHRH1DPP4 | |
| SCHEMBL10967759 | 0.73 | LMNA (0.41) | TAAR1TDP1HTR2AHRH1TSHR | |
| SCHEMBL2320123 | 0.72 | DPP4 (0.41) | TAAR1TDP1HTR2AHRH1DPP4 | |
| Hydrochloric Acid SCHEMBL10435080 | 0.72 | DPP4 (0.48) | TAAR1HTR2AALDH1A1DPP4F2 | |
| SCHEMBL14535430 | 0.70 | KMT2A (0.44) | TAAR1TDP1HRH1ALDH1A1DPP4 | |
| SCHEMBL1145689 | 0.70 | KMT2A (0.44) | TAAR1TDP1HRH1ALDH1A1DPP4 | |
| SCHEMBL20809867 | 0.70 | KMT2A (0.44) | TAAR1TDP1HRH1ALDH1A1DPP4 | |
| SCHEMBL1575568 | 0.70 | TSHR (0.52) | TAAR1TDP1HTR2AHRH1DPP4 | |
| Isopropylbenzene SCHEMBL28691093 | 0.69 | ALDH1A1 (0.48) | TAAR1TDP1ALDH1A1DPP4TSHR | |
| SCHEMBL329800 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499521-A1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-08-19 | — | — | EP | claimed |
| EP-0055444-B1 | TRISUBSTITUTED PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |
| US-4478833-A | ANTICOAGULANTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0055444-A2 | Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-07-07 | — | — | EP | disclosed |