SCHEMBL10968258

SCHEMBL10968258

CCO[Si](CC)(CCCCl)Oc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.36
RELA Q04206 1/20 0.33
KCNA3 P22001 1/20 0.33
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
HTR1B P28222 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA7 P36544 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3888589 0.83 LTA4H (0.41) LTA4HRELAKCNA3SMN1; SMN2L3MBTL1
SCHEMBL19816819 0.80 LTA4H (0.42) LTA4HRELAKCNA3RECQLSMN1; SMN2
SCHEMBL705625 0.79 LTA4H (0.38) LTA4HKCNA3RECQLHTR1BL3MBTL1
SCHEMBL706553 0.79 LTA4H (0.38) LTA4HKCNA3RECQLHTR1BL3MBTL1
SCHEMBL19816531 0.79 LTA4H (0.42) LTA4HSMN1; SMN2
SCHEMBL19816623 0.78 LTA4H (0.41) LTA4HSMN1; SMN2
SCHEMBL963461 0.77 TSHR (0.33) TDP1
SCHEMBL319876 0.77 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL7992033 0.77 LTA4H (0.38) LTA4HKCNA3RECQLSMN1; SMN2HTR1B
SCHEMBL10627368 0.76 LTA4H (0.38) LTA4HRELAKCNA3SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4524169-A THERMOPLASTIC RUBBER, SILICATE FILLER, AND AN ORGANOSILICON COMPOUND DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-06-18 US disclosed
US-4222915-A Vulcanizable halorubber mixtures DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-09-16 US disclosed