SCHEMBL319876

SCHEMBL319876

CCO[Si](CCCCl)(Cc1ccccc1)OC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19809163 0.84 TP53 (0.34) SMN1; SMN2TP53
SCHEMBL19809283 0.84 TP53 (0.39) SMN1; SMN2TP53
SCHEMBL19809224 0.82 TP53 (0.38) SMN1; SMN2TP53
SCHEMBL15303080 0.79 SMN1; SMN2 (0.36) SMN1; SMN2TP53
SCHEMBL3341512 0.79 TP53 (0.38) TP53
SCHEMBL2806315 0.78 TP53 (0.44) TP53
SCHEMBL16756623 0.78 MAOA (0.41) SMN1; SMN2TP53
SCHEMBL15302747 0.77 SMN1; SMN2 (0.37) SMN1; SMN2TP53
SCHEMBL10968258 0.77 LTA4H (0.36) SMN1; SMN2
SCHEMBL534257 0.76 TP53 (0.42) SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10221200-B2 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2019-03-05 US disclosed
US-9796738-B2 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2017-10-24 US disclosed
US-20170233416-A1 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2017-08-17 US disclosed
EP-2590988-B1 QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE EVONIK DEGUSSA GMBH (DE) 2017-03-01 EP disclosed
CN-103080117-B Season amino alcohol official can organo-silicon compound, compositions containing this compound and their preparation and purposes 赢创德固赛有限公司 2016-08-03 CN disclosed
CN-102405224-B Comprise composition and the Synthesis and applications thereof of season amino-functional silicoorganic compound EVONIK DEGUSSA GMBH (DE) 2015-12-16 CN disclosed
EP-2421874-B1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2015-09-30 EP disclosed
US-8980960-B2 Methods for producing a dispersion containing silicon dioxide particles and cationization agent EVONIK DEGUSSA GMBH (DE) 2015-03-17 US disclosed
US-8979996-B2 Composition containing quaternary amino-functional organosilicon compunds and production and use thereof EVONIK DEGUSSA GMBH (DE) 2015-03-17 US disclosed
US-20140208981-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2014-07-31 US disclosed
CN-102405263-A Dispersion containing silicon dioxide particles surface-modified with quaternized amino-functional organosilicon compounds EVONIK DEGUSSA GMBH 2012-04-04 CN disclosed
CN-102405224-A Compositions comprising quaternary amino-functional organosilicon compounds, their preparation and use EVONIK DEGUSSA GMBH 2012-04-04 CN disclosed
EP-2421874-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF Evonik Degussa GmbH (DE) 2012-02-29 EP disclosed
EP-2421921-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS Evonik Degussa GmbH (DE) 2012-02-29 EP disclosed
US-20120037040-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2012-02-16 US disclosed
WO-2012004044-A1 METHODS FOR PRODUCING A DISPERSION CONTAINING SILICON DIOXIDE PARTICLES AND CATIONIZATION AGENT EVONIK DEGUSSA GMBH (DE) 2012-01-12 WO disclosed
US-20120006228-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2012-01-12 US disclosed
WO-2010121878-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2010-10-28 WO disclosed
WO-2010121873-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2010-10-28 WO disclosed
US-4390712-A Aqueous solution of cationic organosilicon compounds and process for the production of the solutions DEGUSSA AG (DE) 1983-06-28 US disclosed