SCHEMBL7992033

SCHEMBL7992033

CC[Si](CC)(CCCCl)Oc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.38
KCNA3 P22001 1/20 0.38
RECQL P46063 1/20 0.35
HTR1B P28222 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
CHRNB2 P17787 2/20 0.33
CHRNB4 P30926 2/20 0.33
CHRNA3 P32297 2/20 0.33
CHRNA7 P36544 2/20 0.33
CHRNA4 P43681 2/20 0.33
ESR1 P03372 2/20 0.32
CHRM2 P08172 2/20 0.32
HTR1A P08908 2/20 0.32
ADRA2A P08913 2/20 0.32
ADORA3 P0DMS8 2/20 0.32
CHRM1 P11229 2/20 0.32
DRD2 P14416 2/20 0.32
ADRA2B P18089 2/20 0.32
ADRA2C P18825 2/20 0.32
CHRM3 P20309 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704094 0.89 LTA4H (0.38) LTA4HKCNA3RECQLHTR1BL3MBTL1
SCHEMBL704883 0.89 LTA4H (0.38) LTA4HKCNA3RECQLHTR1BL3MBTL1
SCHEMBL705618 0.85 LTA4H (0.39) LTA4HKCNA3RECQLL3MBTL1CHRNB2
SCHEMBL713108 0.80 CA4 (0.42) LTA4HKCNA3HTR1BL3MBTL1CHRNB2
SCHEMBL9843707 0.78 ALDH1A1 (0.33) LTA4HKCNA3L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL3923262 0.78 KCNA3 (0.40) LTA4HKCNA3RECQLHTR1BL3MBTL1
SCHEMBL3923699 0.78 KCNA3 (0.40) LTA4HKCNA3RECQLHTR1BL3MBTL1
SCHEMBL3923803 0.77 KCNA3 (0.43) LTA4HKCNA3RECQLHTR1BL3MBTL1
SCHEMBL706648 0.77 LTA4H (0.47) LTA4HKCNA3RECQLESR1CHRM2
SCHEMBL10968258 0.77 LTA4H (0.36) LTA4HKCNA3RECQLHTR1BL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5834536-A REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE BAYER AG (DE) 1998-11-10 US claimed
US-6277902-B1 RUBBER COMPOUNDS COMPRISING SOLUBLE RUBBER, HYDROPHOBIZED FILLER HAVING SPECIFIED METHANOL WETTABILITY, SUPPORTEDPOLYSULFIDIC-SILANE COMPOUNDS PREPARED BY REACTION OF HALOALKYLSILANES, ORGANIC HALOGEN COMPOUNDS AND POLYSULFIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-08-21 US disclosed
US-5834536-A REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE BAYER AG (DE) 1998-11-10 US disclosed
US-5770754-A Method of preparing polysulphidic silyl ethers BAYER AKTIENGESELLSCHAFT (DE) 1998-06-23 US disclosed