Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | GSTO1 | P78417 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GCK | P35557 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557295 | 0.81 | SMN1; SMN2 (0.50) | MAPK1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10968523 | 0.80 | MAPT (0.47) | MAPK1GSTO1MAPTALDH1A1MEN1 | |
| SCHEMBL10967054 | 0.78 | TYR (0.52) | MAPK1GSTO1MAPTALDH1A1MEN1 | |
| SCHEMBL10965770 | 0.77 | SLC2A1 (0.54) | GSTO1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10963568 | 0.76 | RAB9A (0.65) | MAPK1GSTO1MAPTALDH1A1MEN1 | |
| SCHEMBL10961894 | 0.75 | GSTO1 (0.46) | GSTO1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3823589 | 0.75 | MAPT (0.72) | MAPK1GSTO1MAPTALDH1A1MEN1 | |
| SCHEMBL10962068 | 0.74 | MAPT (0.58) | MAPK1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10966433 | 0.74 | HDAC3 (0.67) | MAPK1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10809913 | 0.73 | MAPT (0.57) | MAPK1GSTO1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068033-B1 | N-(4-PHENYL-2-THIAZOLYL)CARBAMATE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (JP) | 1985-07-10 | — | — | EP | disclosed |
| US-4511574-A | IMMUNOMODULATORS | MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (JP) | 1985-04-16 | — | — | US | disclosed |
| EP-0068033-A1 | N-(4-PHENYL-2-THIAZOLYL)CARBAMATE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (JP) | 1983-01-05 | — | — | EP | disclosed |