Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10373748 | 0.91 | KDM4E (0.53) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL10774670 | 0.88 | EPHX2 (0.41) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL9479300 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL9372964 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL8901038 | 0.81 | EPHX2 (0.41) | EPHX2NR1H4 | |
| SCHEMBL9479108 | 0.79 | EPHX2 (0.58) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL9478035 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL9633663 | 0.78 | MTNR1A (0.38) | NR1H4 | |
| SCHEMBL8998286 | 0.77 | EPHX2 (0.56) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL9479292 | 0.77 | EPHX2 (0.56) | KDM4EALDH1A1HPGDLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179619-A1 | Heterocyclic amides | ICI AMERICAS INC. (US) | 1986-04-30 | — | — | EP | disclosed |