⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10969487 | 0.58 | — | — | |
| SCHEMBL158499 | 0.58 | — | — | |
| SCHEMBL9600805 | 0.58 | — | — | |
| SCHEMBL2491334 | 0.58 | — | — | |
| SCHEMBL9512592 | 0.58 | — | — | |
| SCHEMBL8347906 | 0.58 | — | — | |
| SCHEMBL2809033 | 0.50 | — | — | |
| SCHEMBL14564664 | 0.49 | — | — | |
| SCHEMBL9417306 | 0.46 | — | — | |
| Iodide SCHEMBL21465023 | 0.44 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075438-A | Synthesis of azetidinones | SCHERING CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |
| US-5053502-A | Anhydro penicillin derivatives | SCHERING CORPORATION (US) | 1991-10-01 | — | — | US | disclosed |
| US-4948885-A | Synthesis of azetidinones | SCHERING-PLOUGH CORP. (US) | 1990-08-14 | — | — | US | disclosed |
| US-4876338-A | Synthesis of azetidinones using CuCl | SCHERING CORPORATION (US) | 1989-10-24 | — | — | US | disclosed |
| US-4767853-A | Synthesis of 1-(allyloxycarbonyl)-methyl-3-(hydroxyethyl)-4-beta-naphthoxythiocarbonylthio-2-azetidinones and hydroxy protected analogs thereof | SCHERING CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |