Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950413 | 0.81 | — | — | |
| SCHEMBL12450880 | 0.65 | CHRM2 (0.39) | — | |
| SCHEMBL14559892 | 0.65 | BRD4 (0.39) | — | |
| SCHEMBL3990750 | 0.62 | CA1 (0.36) | — | |
| SCHEMBL14559874 | 0.62 | — | — | |
| SCHEMBL8045007 | 0.61 | BRD4 (0.31) | — | |
| SCHEMBL10685413 | 0.61 | BRD4 (0.31) | — | |
| SCHEMBL19393931 | 0.58 | KMT2A (0.35) | — | |
| SCHEMBL600282 | 0.58 | BRD4 (0.52) | — | |
| SCHEMBL44131 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047620-B1 | ARYL DIAZABICYCLYL AMIDES, A PROCESS FOR THEIR PREPARATION AND USE | BEECHAM GROUP PLC (GB) | 1985-03-13 | — | — | EP | disclosed |
| EP-0047620-A1 | Aryl diazabicyclyl amides, a process for their preparation and use | BEECHAM GROUP PLC (GB) | 1982-03-17 | — | — | EP | disclosed |