Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844262 | 0.76 | SLC5A1 (0.58) | ALDH1A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL9808385 | 0.75 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL11239913 | 0.75 | SLC5A1 (0.54) | ALDH1A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL11526781 | 0.71 | NPC1 (0.56) | ALDH1A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL457057 | 0.71 | SLC5A1 (0.65) | ALDH1A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL10971703 | 0.69 | GAA (0.54) | ALDH1A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL12330301 | 0.68 | NPC1 (0.70) | ALDH1A1MAPTKEAP1NPC1RAB9A | |
| SCHEMBL27889179 | 0.68 | RECQL (0.62) | ALDH1A1KEAP1CYP1A1CYP1B1NPC1 | |
| SCHEMBL30572 | 0.68 | TDP1 (0.77) | ALDH1A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL15524969 | 0.68 | TDP1 (0.77) | ALDH1A1GAAMAPTSLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053603-B1 | 1-(3-(2-HYDROXY-3-ALKYLAMINOPROPOXY)-2-THIENYL)-3-PHENYL-1 PROPANONES AND THEIR ACID ADDITION SALTS, AND PROCESS FOR THEIR PREPARATION | Laevosan-Gesellschaft m.b.H. & Co KG (AT) | 1985-04-03 | — | — | EP | disclosed |
| US-4352819-A | ANTIARRHYTHMIA AGENTS | LAEVOSAN-GESELLSCHAFT MBH & CO. KG (AT) | 1982-10-05 | — | — | US | disclosed |