SCHEMBL1844262

SCHEMBL1844262

Cc1c(O)c(C)c(O)c(C(=O)CCc2ccccc2)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 3/20 0.58
SLC5A2 P31639 3/20 0.58
GAA P10253 1/20 0.58
MAPT P10636 1/20 0.58
ALDH1A1 P00352 1/20 0.52
KEAP1 Q14145 1/20 0.50
CYP1A1 P04798 1/20 0.49
CYP1B1 Q16678 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
KCNA3 P22001 2/20 0.48
ACHE P22303 1/20 0.47
SGMS1 Q86VZ5 1/20 0.47
SGMS2 Q8NHU3 1/20 0.47
FFAR1 O14842 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CBS P35520 1/20 0.45
ALOX5 P09917 1/20 0.45
PLA2G2A P14555 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Angoletin SCHEMBL29494768 0.87 KCNA3 (0.59) SLC5A1SLC5A2GAAMAPTALDH1A1
SCHEMBL31237673 0.87 SLC5A1 (0.49) SLC5A1SLC5A2GAAMAPTALDH1A1
SCHEMBL457057 0.84 SLC5A1 (0.65) SLC5A1SLC5A2GAAMAPTALDH1A1
SCHEMBL14400965 0.78 FASN (0.67) SLC5A1SLC5A2GAAMAPTNPC1
SCHEMBL24842064 0.77 ACHE (0.75) SLC5A1SLC5A2GAAMAPTALDH1A1
SCHEMBL11576518 0.76 SLC5A1 (0.54) SLC5A1SLC5A2GAAMAPTALDH1A1
SCHEMBL10969876 0.76 ALDH1A1 (0.47) SLC5A1SLC5A2GAAMAPTALDH1A1
SCHEMBL11526781 0.75 NPC1 (0.56) SLC5A1SLC5A2GAAMAPTALDH1A1
SCHEMBL11577301 0.74 SLC5A1 (0.53) SLC5A1SLC5A2GAAMAPTALDH1A1
SCHEMBL29929379 0.74 KCNA3 (0.67) SLC5A1SLC5A2GAAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2320726-B1 USE OF A MYRICA GALE PLANT FOR THE PRODUCTION OF AN HERBICIDAL AGENT. UNIVERSITÉ CLAUDE BERNARD LYON I (FR) 2017-03-08 EP claimed
US-8734858-B2 Use of a myrica gale plant for producing a herbicide agent UNIVERSITE CLAUDE BERNARD LYON I (FR) 2014-05-27 US claimed
US-20110201503-A1 USE OF A MYRICA GALE PLANT FOR PRODUCING A HERBICIDE AGENT UNIVERSITE CLAUDE BERNARD LYON I (FR) 2011-08-18 US claimed
EP-2320726-A2 USE OF A MYRICA GALE PLANT FOR THE PRODUCTION OF AN HERBICIDAL AGENT. University Claude Bernard Lyon I (FR) 2011-05-18 EP claimed
WO-2010012945-A2 USE OF A PLANT MYRICA GALE FOR PRODUCING A HERBICIDE AGENT UNIVERSITE CLAUDE BERNARD LYON I (FR) 2010-02-04 WO claimed
EP-2320726-B1 USE OF A MYRICA GALE PLANT FOR THE PRODUCTION OF AN HERBICIDAL AGENT. UNIVERSITÉ CLAUDE BERNARD LYON I (FR) 2017-03-08 EP disclosed
US-8734858-B2 Use of a myrica gale plant for producing a herbicide agent UNIVERSITE CLAUDE BERNARD LYON I (FR) 2014-05-27 US disclosed
US-20110201503-A1 USE OF A MYRICA GALE PLANT FOR PRODUCING A HERBICIDE AGENT UNIVERSITE CLAUDE BERNARD LYON I (FR) 2011-08-18 US disclosed
EP-2320726-A2 USE OF A MYRICA GALE PLANT FOR THE PRODUCTION OF AN HERBICIDAL AGENT. University Claude Bernard Lyon I (FR) 2011-05-18 EP disclosed
WO-2010012945-A2 USE OF A PLANT MYRICA GALE FOR PRODUCING A HERBICIDE AGENT UNIVERSITE CLAUDE BERNARD LYON I (FR) 2010-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201503-A1 USE OF A MYRICA GALE PLANT FOR PRODUCING A HERBICIDE AGENT MGAM, GALC, MGAM2 SLC5A1 459/4885SLC5A2 279/4885GAA 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.