Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 7/20 | 0.60 |
| ▸ | PPARA | Q07869 | 7/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754768 | 0.96 | PPARD (0.58) | PPARDPPARGPPARAPTGS2ALDH1A1 | |
| SCHEMBL11752001 | 0.96 | PPARD (0.58) | PPARDPPARGPPARAPTGS2ALDH1A1 | |
| SCHEMBL11754185 | 0.94 | PPARD (0.61) | PPARDPPARGPPARAPTGS2LMNA | |
| SCHEMBL11754256 | 0.94 | PPARD (0.61) | PPARDPPARGPPARAPTGS2LMNA | |
| SCHEMBL11040651 | 0.91 | PPARD (0.56) | PPARDPPARGPPARAPTGS2ALDH1A1 | |
| SCHEMBL10797270 | 0.88 | PPARG (0.61) | PPARDPPARGPPARAPTGS2ALDH1A1 | |
| SCHEMBL11753666 | 0.86 | PPARG (0.48) | PPARDPPARGPPARAPTGS2ALDH1A1 | |
| SCHEMBL10969883 | 0.86 | PPARG (0.66) | PPARDPPARGPPARAPTGS2ALDH1A1 | |
| SCHEMBL9729986 | 0.85 | ALDH1A1 (0.65) | PPARDPPARGPPARAPTGS2ALDH1A1 | |
| SCHEMBL11747943 | 0.85 | PPARD (0.45) | PPARDPPARGPPARAPTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711879-A | IMMUNO-MODULATING ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1987-12-08 | — | — | US | claimed |
| US-4640911-A | IMMUNOSTIMULANTS, VIRICIDES SUCH AS HERPES SIMPLEX | CIBA-GEIGY CORPORATION (US) | 1987-02-03 | — | — | US | claimed |
| US-4711879-A | IMMUNO-MODULATING ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1987-12-08 | — | — | US | disclosed |
| US-4640911-A | IMMUNOSTIMULANTS, VIRICIDES SUCH AS HERPES SIMPLEX | CIBA-GEIGY CORPORATION (US) | 1987-02-03 | — | — | US | disclosed |
| US-4451471-A | Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |