Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 8/20 | 0.57 |
| ▸ | PPARA | Q07869 | 7/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754768 | 1.00 | PPARD (0.58) | PPARDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10801302 | 0.96 | PPARD (0.61) | PPARDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11754185 | 0.91 | PPARD (0.61) | PPARDKMT2APPARGPPARAPTGS2 | |
| SCHEMBL11754256 | 0.91 | PPARD (0.61) | PPARDKMT2APPARGPPARAPTGS2 | |
| SCHEMBL11042391 | 0.90 | PTGS2 (0.54) | PPARDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11040651 | 0.87 | PPARD (0.56) | PPARDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11751372 | 0.86 | PPARD (0.51) | PPARDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11754137 | 0.86 | PPARD (0.51) | PPARDALDH1A1MAPTPPARGPPARA | |
| SCHEMBL11753338 | 0.86 | PTGS2 (0.48) | PPARDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11751179 | 0.86 | PTGS2 (0.48) | PPARDMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |