Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.63 |
| ▸ | DAO | P14920 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366351 | 0.88 | DAO (0.65) | KDM4EALDH1A1GAAPOLBPIN1 | |
| SCHEMBL10330642 | 0.87 | DAO (0.63) | KDM4EALDH1A1GAAPOLBPIN1 | |
| SCHEMBL22223088 | 0.83 | DAO (0.58) | KDM4EALDH1A1GAAPOLBPIN1 | |
| SCHEMBL12082628 | 0.83 | ALDH1A1 (0.61) | KDM4EALDH1A1GAAPOLBPIN1 | |
| SCHEMBL15564491 | 0.82 | DAO (0.54) | KDM4EALDH1A1GAAPOLBPIN1 | |
| SCHEMBL2806050 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL29415468 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL4649667 | 0.81 | DAO (0.52) | KDM4EALDH1A1GAAPOLBPIN1 | |
| SCHEMBL8500109 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1GAAPOLBDAO | |
| SCHEMBL2310250 | 0.80 | F7 (0.63) | KDM4EALDH1A1GAAPOLBDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073507-B1 | SULFONYL UREAS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-16 | — | — | EP | disclosed |
| US-4542139-A | HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-17 | — | — | US | disclosed |
| EP-0073507-A1 | Sulfonyl ureas, process for their preparation, pharmaceutical compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-09 | — | — | EP | disclosed |