Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23806 | 0.82 | — | — | |
| SCHEMBL10970 | 0.82 | — | — | |
| SCHEMBL29368123 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL10879894 | 0.80 | CYP2A6 (0.40) | LMNACYP2A6NAMPTCYP2E1CYP3A4 | |
| Hydrochloric Acid SCHEMBL10877970 | 0.80 | CYP2A6 (0.40) | LMNACYP2A6NAMPTCYP2E1CYP3A4 | |
| SCHEMBL30048909 | 0.80 | ALDH1A1 (0.46) | LMNACYP2A6ABCB1ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6309590 | 0.80 | ALDH1A1 (0.46) | LMNACYP2A6ABCB1ALDH1A1HSD17B10 | |
| SCHEMBL29894511 | 0.80 | ALDH1A1 (0.46) | LMNACYP2A6ABCB1ALDH1A1HSD17B10 | |
| SCHEMBL28027613 | 0.80 | ALDH1A1 (0.46) | LMNACYP2A6ABCB1ALDH1A1HSD17B10 | |
| Ethane SCHEMBL28746668 | 0.79 | ALDH1A1 (0.45) | LMNACYP2A6ABCB1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1020340-C | 1-carbacephalosporin antibiotics | LILLY CO ELI (US) | 1993-04-21 | — | — | CN | disclosed |
| CN-86108961-A | 1-CARBACEPHALOSPORIN ANTIBIOTICS | — | 1987-08-05 | — | — | CN | disclosed |